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In the twenty-first century, particularly after 2010, advances in high-throughput sequencing technologies enabled genome-wide profiling of epigenetic landscapes, revealing their dynamic remodeling in response to diverse therapeutic pressures [12]

By utilizing virtual screening techniques, we have successfully conducted a comprehensive screening of a natural compound known as Urolithin A (UA), which exhibits remarkable inhibition of osteoblastic ferroptosis while simultaneously promoting the process of osteogenesis through its precise targeting mechanism on GPX4

Isolation and characterization of activated macrophages

Cannabinoid ligands targeting TRP channels

Macrophage receptors and immune recognition