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During the early stages of PD, [11C]BU99008 PET showed an increased uptake in frontal, temporal, parietal, occipital and insula cortices and subcortical regions such as caudate, putamen, thalamus and brainstem as compared with healthy controls, whereas in advanced stages these differences disappeared 365

Park J, Song W-Y, Ko D, Eom Y, Hansen TH, Schiller M, et al

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Further reading [edit] Pharmacology

We dose based on your weight, oxidative stress markers, and treatment goals, not a one size fits all protocol