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The hallmark of defective proteostasis in ALS is cytoplasmic ubiquitinated protein inclusions (such as TDP-43 or FUS) [211, 214]

Food Engineering, Universidade Federal de Minas Gerais (UFMG)

Efficacy and cost-effectiveness of nurse-led care involving education and engagement of patients and a treat-to-target urate-lowering strategy versus usual care for gout: a randomised controlled trial