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Mitochondrial dysfunction Disruption of mitochondrial defense mechanisms is mediated by the Parkin and PTEN-induced kinase 1 (PINK1) genes which are critical for mitophagy, a process that removes dysfunctional mitochondria from cells

This improvement in exercise capacity can lead to more effective workouts, which in turn can contribute to increased fat loss and muscle gain over time

39 The present investigation observed significantly increased serum concentrations of AST, ALT, and ALP in rats with T2DM induced by STZ and HFD compared to control rats

514 UPR signaling in neuroinflammation, oligodendrocyte survival, and demyelination in MS ER stress is widely observed in demyelinating lesions in MS, with elevated levels of markers such as CHOP, BiP, phosphorylated PERK, phosphorylated eIF2, and XBP-1 in microglia, oligodendrocytes (OLs), T cells, and astrocytes

(eds) Basic Protocols in Foods and Nutrition