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The predictors of pemetrexed toxicities were poor Eastern Cooperative Oncology Group performance status (ECOG-PS) and low body mass index (BMI) for febrile neutropenia (FN), concomitant chronic infectious disease, bevacizumab use for neutropenia, poor ECOG-PS for thrombocytopenia, and low serum albumin levels for non-hematologic toxicities

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Throw away any unused medicine after the beyond-use date

Deficiency in B12 can cause symptoms of anaemia, fatigue, constipation poor memory and reduced mental function