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The specific rotation of acetyl L-carnitine hydrochloride is as follows: [64] Specific rotation [] 25 = -28 (C=I, H O) [65] Industrial Applicability [66] As can be seen from Examples 1 through 5, a process for preparing L-carnitine or acetyl L-carnitine hydrochloride in accordance with the present invention employs a very inexpensive material as a starting material and involves a simplified reaction process in conjunction with a capability to prepare an intermediate having a high optical purity at a low production cost

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Inhibiting the GAT-1 transporter, thereby allowing further release of GABA and enhancing neural inhibition, reduced paclitaxel-induced neuropathic pain

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