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Within lysosomes, iron is normally reduced and recycled back to the cytoplasm via TRPML1 or DMT1 to meet metabolic demands ( 2+ levels and suppressing Fenton reactiondriven oxidative stress and ferroptosis

Both are studied for cell migration and actin regulation in tissue-repair models

6.2 Autophagy induction is an evolutionarily conserved function of the cGAS-STING signal Earlier studies have mainly focused on the mechanism of IFN induction by the cGAS-STING pathway

Furthermore, we identified Pediococcus acidilactici GR-6 and Lactobacillus fermentum GR-7, isolated from crucian carp gut, that synergistically synthesize vitamin B 6 de novo during pathogens co-culture, achieving 63% inhibition of polymicrobial pathogens