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A key consideration of exosomes is that the challenges in extracting biological fluid-derived exosomes, for example, in plasma, where enrichment of biological molecules and various exosome species exists, thereby an issue like the corona effect occurs (Voke et al., 2025)

Beyond BBB penetration, the selection of DDS in AD should also consider disease-specific pathological features that may affect therapeutic access and efficacy

Very rarely, individuals might have an allergic reaction symptoms would include hives, difficulty breathing, or swelling of the face and throat

It uses a combination of mild cleansing agents (cetrimonium chloride, cetylpyridinium chloride, hexylene glycol, peg-6 caprylic/capric glycerides) and should be able to cleanse the skin gently

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