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At the N-terminus, it has its catalytic active site with a Rossmann dinucleotide fold interacting with the 2 OH of the final nucleotide of tRNA Gln (A76), while the C-terminus interacts with the tRNAs anti-codon loop

Science 250 , 10021004 (1990)

Using the average body weight of a cat and average consumption, 175 mM/kg/d total GLY was fed in the GLY feeding study

Aberrant cGAS-STING activation leads to excessive and sustained production of type I interferon, which mediates local or systemic inflammation and is thus involved in the development of many inflammatory disease processes (92)

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