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Following an initial event of RCD, DAMPs accumulation can trigger tissue inflammation which can further promote RCD to form a self-amplified circuit of necro-inflammatory loop that leads to exaggerated cell death and inflammation, eventually resulting in tissue damage and organ dysfunction [48, 49]

In Atlantic salmon the ratio was 66:20:14 in fish fed a marine diet (Nimalan et al., 2022), and in grass carp it was 70:15:15 in fish fed a control FM diet, though both amount and ratio was shown to change upon alteration of feed, resulting from the altered GM that followed (Hao et al., 2017a)

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Arginine-modifying enzymes in pulmonary fibrosis Beyond its metabolic roles, arginine is subject to post-translational modifications, such as methylation and citrullination, which significantly impact pulmonary fibrosis

LOX3 negatively regulates induced systemic resistance to C