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This multitiered defence system comprises an endogenous antioxidant enzyme system (e.g., SOD/CAT/GPx) and small-molecule free radical scavengers such as vitamin C/E and -carotene, which are supported by trace elements such as selenium and zinc, collectively maintaining redox homeostasis [18]

While some metals, like as copper and zinc, are required in tiny amounts, high doses can be hazardous

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