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Leaf size, however, is age-dependent and, thus, older plants may be preferred for the investigation of mature trichomes

91 Recent reviews that examined isoflavonoids and the health of postmenopausal women concluded that a) adding soy foods or phytoestrogens to the diet can contribute to the health of postmenopausal women, 91,101103 b) isoflavones or phytoestrogens do not increase the risk of breast, endometrial or colorectal cancer, 91,102,103 and c) the research evidence does not support classifying isoflavones as endocrine disruptors

Selected manuscripts were matched to the PICO questions (see Supplementary Information section D)