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Direct tissue temperature measurements suggested that therapeutic freezing may not have extended across the full diameter of the sciatic nerve, highlighting a key technical limitation that may explain the lack of clinical benefit

10.4161/auto.6398 92 KocarnikJ

You can take coffee or tea at a cooler temperature during the first three days after the procedure

Taken together, our data indicate that the loss of GSH triggered by Gclc deletion induces a defective mitochondrial accumulation in FoB, which may lead to compensation through upregulation of glycolytic metabolism