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Concurrently, they suppress CYP2E1 activity, limiting acetaldehyde-induced ROS generation, and inhibit TLR4/MyD88 signaling to reduce TNF- and IL-6 secretion (Nagappan et al., 2019

Second, transcriptomic analyses do not identify other possible regulatory mechanisms that may operate during oxidative stress at the post-transcriptional or post-translational levels