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Conclusion Current research on DPN biomarkers encompasses a diverse array of candidates, including oxidative stress mediators, neural injury proteins, inflammatory cytokines, vascular dysfunction markers, metabolic intermediates, and genetic/epigenetic regulators

The study, published in Nature Molecular Psychiatry , found that participants with higher levels of glutathione responded more quickly to their antipsychotic medication

Individuals with conditions such as pernicious anemia, gastrointestinal disorders, or post-surgical digestive changes may lack sufficient intrinsic factor, making oral absorption inefficient

doi: 10.1038/s41467-022-30836-0 170 SudreCHMurrayBVarsavskyTGrahamMSPenfoldRSBowyerRCet al

281,282 Liver-specific KO of upstream Hippo kinases, including MST1/2, LATS1/2, and the adaptor proteins SAV1 and MOB1a/b, leads to decreased YAP phosphorylation and increased nuclear translocation