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One aspect of this study that may be missed are the overall excellent responses achieved with only a moderate dose of methotrexate, highlighting the potency of methotrexate as a DMARD which can often be overlooked in clinical trials that typically enroll only subjects with inadequate responses to methotrexate

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Unvaccinated individuals with prior Omicron infection had the lowest PASC incidence (OR 0.14, 95% CI 0.070.25), while vaccination did not reduce PASC risk

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