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Meanwhile, glutaredoxin-1 (GLRX1) can rescue the loss of TXNRD1 by catalyzing the transfer of electrons from GSH to TRX

Curcumin prevents high-fat diet-induced hepatic steatosis in apoe/ mice by improving intestinal barrier function and reducing endotoxin and liver tlr4/nf-b inflammation

TABLE 1 Gut microbiota dysbiosis and gastrointestinal disease

In addition to exceptional absorption rates, small liposomal and nanoemulsified particles enhance lymphatic circulation, helping to bypass digestive enzymes and breakdown in the liver

They exhibit excellent biocompatibility, biodegradability, and low immunogenicity, and are capable of encapsulating hydrophilic, lipophilic, and hydrophobic substances, making them ideal carriers for drug delivery (Topal et al., 2020)