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Description

Koppula P, Zhuang L, Gan B

The resulting histamine overload causes systemic inflammation, leading to classic MCAS symptoms like sudden hives, flushing, severe gastrointestinal distress, rapid heart rate (tachycardia), and sudden intolerances to previously safe foods

Dopaminergic disruption by oxysterols is also observed in psychiatric disorders such as schizophrenia (Sun et al., 2021) and depression (Sun et al., 2023)