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Athletes should consult their sport's governing body and anti-doping authority before considering any peptide supplement

Note on amyloid aggregation: Cagrilintide has proline substitutions at positions 25, 28, 29 , which dramatically reduce the amyloidogenic potential

In addition to aiding in cell permeability (Fig S2A), we speculated that enhancing helicity would improve solubility by preventing -sheet based peptide aggregation