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While the ultimate goal of the geroscience approach is to extend healthy lifespan by delaying or preventing disease, the lack of specific biomarkers for senescent cells (fluid, imaging, etc.) represents a major hurdle for identifying participants that may most benefit from senolytics

And low levels of glutathione are present in atherosclerotic lesions, caused by an antioxidant/prooxidant imbalance, as well as high homocysteine levels

Extended semen was packaged into 0.25 mL French mini-straws (IMV, France), equilibrated at 5 C for 4 h, frozen in liquid nitrogen (196 C) for at least one week, and thawed at 37 C for 30 s before evaluation

The detailed composition of these diets appears in a recent publication 46

L., Byrd, R