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Although its not required in substantial amounts, vitamin B12 plays several big roles (3): Energy production Red blood cell formation (hematopoiesis) DNA synthesis Brain development Nervous system function Fatty acid synthesis Myelin formation Cardiovascular health But the thing with vitamin B12 is that although a deficiency takes a significant amount of time to develop, certain groups are more susceptible to a deficiency than others

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A compounding pharmacy, working with smaller batches and different equipment, assigns a more conservative date because they have less long-term data to support extended shelf life claims

In other words, vitamin B12 may be important for cellular immunity, especially for CD8 + cells and the NK cell system [50]

Using the clinical trial escalation protocol (2mg starting dose with 2mg increases every 4 weeks), reaching the 12mg maintenance dose takes approximately 20 weeks