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Another important function of SMAC mimetics is sensitization of cancer cells to TNF--induced cell death

2011:7589.Google Scholar Gulati, G, OHara, JF, Krause, J

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Barch DM, Braver TS, Carter CS, Poldrack RA, Robbins TW

In dopaminergic neurodegenerative disorders, a key pathogenetic event is also the inactivation of tyrosine hydroxylase, a rate-limiting enzyme in dopamine and norepinephrine biosynthesis, by oxidative injury (Di Giovanni et al., Mutations of the antioxidant superoxide dismutase gene (SOD1) are linked to about one fifth of the cases of familial amyotrophic lateral sclerosis, a degenerative disorder of motor neurons