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Furthermore, we observed an enhanced degradation of nucleotide bases, as reflected in lower levels of xanthosine 5-triphosphate and subsequent accumulation of purine (i.e., hypoxanthine, uric acid, 5-hydroxyisouric acid, allantoin) and pyrimidine (i.e., ureidosuccinic acid, N-acetylcytidine) catabolites

After the final wash, the pellet was resuspended in 40 l of 1x electrophoresis sample buffer (40% glycerol, 240 mM Tris/HCl pH 6.8, 8% SDS, 0.04% bromophenol blue, 5% -mercaptoethanol) and analyzed by SDS-PAGE western blot

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According to a study, after a single injection of CJC-1295, mean plasma growth hormone concentrations increased dose-dependently by 2- to 10-fold for 6 days or longer, and mean plasma IGF-I concentrations increased by 1.5- to 3-fold for 911 days