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The mean sperm DFI was increased across all study groups (range, 40.6%44.0%), indicating impaired fertility capability among the CP/CPPS cohorts

IGF-1 LR3 is an exogenous receptor agonist applied at the very endpoint of the axis, bypassing the feedback loop entirely

[DOI] [PMC free article] [PubMed] [Google Scholar] 136.Mezzadra R, Sun C, Jae LT, Gomez-Eerland R, de Vries E, Wu W, Logtenberg MEW, Slagter M, Rozeman EA, Hofland I, et al