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Arshad, A

While swelling is necessary for proper wound healing, too much or prolonged swelling can impair healing and lead to chronic wounds

These results suggest that upon depletion of GSH, tissues undergo reprogramming to hyperactivate NRF2, possibly as a mechanism to upregulate adjacent antioxidant pathways and buffer oxidative stress induced upon GSH depletion

Faerron Guzman Planetary Health Alliance, Johns Hopkins University University of Maryland Baltimore Graduate School Catherine Machalaba The Nature Conservancy Cedric Colmar Director of partnerships, international and European affairs - VetAgro Sup Moderators: Olakunle Alonge, Anna Hellova Implementation research has a potential to tackle a variety of global health challenges

2 The redox state of the cytoplasmic [NADPH]/[NADP + ] and [NAD + ]/[NADH] are linked in cells with high malic enzyme 1 (ME1) and LDH activities In cells with at least moderate cytoplasmic malic enzyme 1 (ME1) activity, the malate/pyruvate is proportional to the cytoplasmic [NADPH]/[NADP + ] (Veech et al., 2019)