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These modular models can subsequently be integrated into a comprehensive framework to rationally design NM-active ingredient combinations that enhance NUE, reduce environmental pollution, increase crop yield, and potentially improve nutritional (calorific) value [28] However, the successful application of AI and ML models in agriculture is fundamentally dependent on the availability of high-quality, well-annotated datasets capturing the interactions of NPs of diverse sizes, shapes, surface chemistries, and compositions with plants, soils, and soil microbiota

SAM and SAH show pathway activity Low SAM and elevated SAH represent different biochemical barriers and should not automatically receive the same treatment