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The research in the laboratory is also was also supported by grants from the NIGMS (P20GM139753 - Sub project 5203) to B.K.S, the National Heart, Lung, and Blood Institute (2T32HL115505-11) to A.G.S, and the Hawaii Community Foundations Ingeborg v.F

Among these, Farnesoid X Receptor (FXR) and Takeda G-protein Receptor 5 (TGR5) represent two critical BAs receptors (Wang et al., 2008)

10.1039/d1na00697e 97 ZhengN.FuY.LiuX.ZhangZ.WangJ.MeiQ.et al (2022)

[64] claimed that if cereals used for making sourdough are grown conventionally, the sourdough starter usually has lower biodiversity than those using flour from organically grown cereals

These advantageous actions of the tested agents were accounted to their antioxidant, anti-inflammatory and anti-apoptotic properties, along with their abilities to modulate HMGB1/RAGE/JAK-2/STAT-3, PI3K/AKT/CREB/BDNF/TrkB, AMPK/SIRT-1/m-TOR and PERK/CHOP/GRP78/Bcl-2 hubs, as main contributors in the underlying pathophysiological mechanisms in MSG-induced ADHD-like behaviors (Graphical abstract)