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Antibodies against PTM of beta-cell autoantigens, such as GAD65 and insulin, may play a critical role in disease onset and development

Inducible nitric oxide synthase during the late phase of sepsis is associated with hypothermia and immune cell migration

In these cases, B12 injections provide a direct and effective method to restore healthy vitamin levels

Kameda M, Teruya T, Yanagida M, Kondoh H

Moderate instability promotes adaptation by enabling oncogene amplifications (e.g., ERBB2, CCND1, MYC) or loss of tumor suppressor loci, facilitating therapeutic escape, whereas excessive instability compromises viability