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Infected cells were cultured under standard conditions, and gene knockdown efficiency was confirmed through Western blot

Over the course of the 6-year study, 81.8% of the patients in the control group died, while only 41.7% of patients in the thymalin group and 45.8% of those in the epithalamin group, both of which received treatment for 2 years, died

Spearmans correlation was performed for analysis between the quantitative covariates and the outcome

Notably, in Lrrk2 G2019S knock-in mice, LRRK2 kinase inhibitors rescue these defects [29]