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Numerous herbal candidates for PD treatment have advanced to clinical trials (Prasad and Hung 2021), with evidence indicating that TCM can significantly alleviate symptoms, improve patients quality of life and maintain a favorable safety profile

& Oja, S

Moreover, beyond the role of tumor suppressor protein p53 in apoptosis, autophagy, and cell cycle, emerging evidence suggests that it sensitizes cells to ferroptosis via the regulation of cystine metabolism and ROS responses [15]