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230,250 For example, celecoxib, a non-steroidal anti-inflammatory drug, targets the cyclooxygenase 2 (COX-2)/AKT pathway and was sufficient to inhibit the progress of HCC by inhibiting lipogenesis

Darinaparsin belongs to the class of organic arsenical compounds that are generally considered less toxic than inorganic ones (Waxman and Anderson, 2001

It can modulate the activity of enzymes involved in the production of inflammatory mediators, such as lipoxygenase and cyclooxygenase, thus reducing oxidative stress and inflammation [215]

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Figure 7 4.1 Lipid-based nanoparticles Lipid-based NPs mainly comprise liposomes and SLNs, which are commonly investigated for treating PD