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GPCR and memory B cells Upon subsequent exposure to systemic antigens, IgG + PC precursors migrate towards CXCR3 ligands, which may facilitate their migration to BM and inflamed tissue respectively [34]

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The ultrastructure of mitochondria-associated endoplasmic reticulum (MAM) is a core regulatory hub, and its dysfunction can cause calcium homeostasis imbalance, mitochondrial energy metabolism disorders and a vicious cycle of oxidative stress [147]