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Following treatment with GHK or GHK-PEG, the number of cells per ml of media was assessed as previously described and the rate of cell proliferation was expressed as fold control and compared between treated and non-treated cells using analysis of variance (ANOVA)

Additionally, the study assessed weight and metabolic responses, finding that efinopegdutides tolerability was similar to that of semaglutide, although certain gastrointestinal side effects were more common

Furthermore, most of the available evidence comes from secondary analyses of diabetes or obesity cohorts, which may not be fully generalizable to patients with established AITD

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