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Comprehensive transcriptome and proteome analyses have provided global views of mRNA and protein abundance of metabolic enzymes in kidney regions and nephron segments 24,25,26,27 , which are generally consistent with results of previous targeted analyses of enzyme activity, protein abundance, or substrate utilization

Acknowledgements The authors would like to express their gratitude to the BRIC-National Agri-Food and Biomanufacturing Institute (Formerly Center of Innovative and Applied Bioprocessing), Department of Biotechnology (DBT), which provided support and motivation throughout this study

66 FPN has also been shown to modulate cell sensitivity to ferroptosis in vitro, 68 and FPN inhibitors can be used to modulate ferroptosis

The results are presented as molar ellipticity [] in degcm 2 dmol 1 units