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Metabolic Health: Protects the kidney against high glucose induced injury in models of diabetic nephropathy via its antioxidant mechanisms

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This is the mechanistic reason researchers study it separately from native IGF-1: with less protein-binding interference, the analog remains bioavailable roughly 3x longer, giving it an extended half-life of approximately 2030 hours compared to native IGF-1s 1215 hours

However, studies have shown that oral B12 (cyanocobalamin) supplementation provides effective acute and maintenance treatment for vitamin B12 deficiency caused by Crohns Disease with or without ileum resection