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A clinical trial of 100 smokers found NAC significantly improved measures of pulmonary health and high-dose NAC taken over a one year period resulted in significantly improved small airway clarity and decreased frequency of respiratory challenges

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Additionally, GSH, SOD, and HDL levels were upregulated, whereas MDA, urea, LDL, TG, CREA, TC, ALP, AST, and ALT levels were downregulated with SHF treatment (Zhang et al., 2018)

This work was granted access to the HPC resources of CINES under the allocation 2020-A0070810977 made by GENCI