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In patients of reproductive age, hormonal fluctuations associated with the menstrual cycle or pregnancy have been reported to affect MdDS symptoms similarly to migraine, with higher symptoms during menses when estrogen is lower and a reduction in symptoms during the first two trimesters of pregnancy, when estrogen and progesterone are higher 5,12

doi:10.1016/S0092-8674(01)00341-5

J., Haycock, J., Dastjerdi, A., Davies, H

Inject DSIP subcutaneously 30 to 60 minutes before your intended sleep time

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