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At the extreme end of this situation, where there is a genetic deficit in carnitine biosynthesis, some nasty stuff happens without carnitine supplementation [1]: Liver damage and dysfunction Brain damage Muscle weakness Lethargy Exercise intolerance Yet, there can also be situations of mild deficiency where these overt signs arent present

* These statements have not been evaluated by the Food and Drug Administration

The datasets generated and analysed during the current study are available in the Gene Expression Omnibus (GEO) server with access number GSE232691

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[DOI] [PMC free article] [PubMed] [Google Scholar] 125.Pitzschke A., Hirt H