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Matricellular proteins, including elastin, fibronectin 4, and fibronectin 5, are primarily expressed in the reticular layer 37,38 and are essential for the formation of elastic fibers

And so, what I found looking into it is the grand majority of the people that are professors in most of the schools, and almost all the branches of medicine are not clinicians, they dont have much skill at actually working in the field

Fibroblast growth factor-2 maintains the differentiation potential of nucleus pulposus cells in vitro : implications for cell-based transplantation therapy