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Andrologia 42:213217

Glial cells improve Parkinson's disease by modulating neuronal function and regulating neuronal ferroptosis

The paper highlights GHK-Cus ability to modulate gene expression, affecting a large number of genes related to tissue repair, anti-cancer activity, anti-inflammatory actions, and DNA repair

Direct involvement of hydrogen peroxide in the activation of NF-B has been discussed ( 102 inhibited the TNF induced activation of NF-B pathway dose-dependently with an EC 50 of 60.8 M ( Figure 6 )

More in-depth research that clarifies the roles of these components of the GST-detoxification system are much needed, in order to produce compounds that have minimal side effects and high GST selectivity