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Other typical agents with reported inhibitory activities on TYR include kojic acid (111,112), methyl gentisate (113,114), ganodermanondiol (71,115), 10-hydroxy-2-decenoic acid (116), Stichopus japonicus extracts (69) and bis (4-hydroxybenzyl)sulphide (117)

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PARP inhibitors have also shown significant synergy with type I PRMT inhibitors in NSCLC and in ovarian cancer, where type I PRMT inhibition re-sensitised resistant PEO4 ovarian cancer cells to PARP inhibitor treatment in vitro (112)

(2018) reported a study in which 71 women with mild to advanced photoaging applied a facial cream containing GHK-Cu for 12 weeks

Crawford and Weerapana reported a dichlorotriazine-containing compound (LAS17) that selectively and irreversibly inhibited GSTP1 activity, thus providing a promising cancer therapeutic target [55]