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Moreover, the inflammatory response can affect the degree of ERS

A large majority of fish oil used to create marine-derived omega-3s come from small, fatty fishes like: sardines, mackerel and anchovies

Critical modulators of ferroptosis exhibit regulatory capability in various PCD pathways

One possible explanation for such a response is that inhibition of mTORC1 and activation of GCN2 collectively suppresses global translation to conserve nutrients, while selective translation of mRNA such as ATF4 (mediated by increased p-eIF2) activates the expression of AARE genes to mitigate cellular stress