thalassemia minor treatment b12 injection β-Thalassemia Gene therapy promotes transfusion independence

Gene therapy promotes transfusion independence for severe beta thalassemia Vitamin B12 deficiency is not rare. It is underdiagnosed and often mismanaged. Daily physiological requirement sits around 2.4 mcg. Correction is a different game. Oral high dose therapy works because about 12% of How to Identify Alpha, Beta, and Trait Thalassemia in the Lab To identify Alpha, Beta, and Trait Thalassemia in the lab, start with a CBC. Look for the "Thalassemia Paradox": a high Pernicious anemia presenting as glossitis with thalassemia JBM Dove Medical Press Current and future alternative therapies for beta thalassemia major PMC

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