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The pyrimidine adducts formed by the attack of hydroxy radical include hydantoin, 5-hydroxy deoxycytidine, 5-hydroxydeoxy uridine, uracil glycol, and thymine glycol, respectively

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Since mutants devoid of GSH ( gsh1 ) or with an altered GSH redox ratio ( glr1 ) were susceptible to H 2 O 2 , GSH is a crucial antioxidant found in yeast cells that plays a vital role in protecting against H 2 O 2 damage (Shao et al., 2019

Once the pigment-producing cells in a follicle are gone, antioxidants can protect the surrounding follicles but may not bring color back to "dead" cells

The metabolite analysis demonstrated that Nrf2 strongly promotes purine nucleotide synthesis, resulting in the increased production of purine nucleotides