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In general, a high ratio of Firmicutes / Bacteroidetes may present as a marker of subclinical AS [204]

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Alternatively, lower levels of NO, produced by endothelial nitric oxide synthase (eNOS), play important roles in preventing platelet adhesion to vessel walls during haemostasis 66 , and for both keratinocyte and fibroblast proliferation, motility, and differentiation at the later proliferation and tissue remodelling stages of wound healing 67,68,69

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