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Side effects are similar to those of intracavernosal injection and include local pain (32%) and, in rare cases, persistent penile pain or priapism

Lidocaine and verapamil are both used to treat cardiac arrhythmias and have bioavailability less than 40%, but lidocaine is never given orally because its metabolites are believed to contribute to central nervous system toxicity

Strenuous physical activity can temporarily increase cholesterol levels, inflammatory markers, and certain enzymes

Angiotensin II-dependent TGF-beta signaling contributes to LoeysDietz syndrome vascular pathogenesis

Nelfinavir induces liposarcoma apoptosis through inhibition of regulated intramembrane proteolysis of SREBP-1 and ATF6