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Development of novel immunotherapies for multiple myeloma

Studies have shown that loading PTX, gemcitabine monophosphate (GEMP), and the intermediate products of gemcitabine metabolism onto EVs can overcome chemotherapy resistance [207]

In one study, some researchers used a CRISPR/Cas9 knockout screen to identify 10 drug-resistant genes, including C1orf115, a previously uncharacterized MDR gene that they named required for drug-induced death 1 (RDD1) (463)

Paired-end sequencing with a read length of 150 base pairs on each end was performed on an Illumina NovaSeq 6000 platform (Illumina, Inc.) with the NovaSeq 6000 S4 Reagent Kit (cat

2013 reported Phase 2 safety/tolerability of the AOD9604 modified form in obesity