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Description

The LIP consists of low-molecular-weight, redox-active iron, mainly Fe 2+ complexed with small ligands such as citrate or adenosine triphosphate (ATP)

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It attenuates ischemia/reperfusion injury by suppressing NLRP3 inflammasome and apoptosis, mitigating ferroptosis via Nur77-IDH1 signaling (Zhang et al., 2020

TCM has own characteristics such as holistic concept, syndrome differentiation and treatment, strengthening the body resistance to eliminate pathogenic factors