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27 Vertebral body fracture without the involvement of the endplate (type A2), the NP or the AF does not directly affect the disc structure, and, hence, the direct biological consequences may be assumed to be similar to injury type A1

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Once reconstituted, the solution should be used promptly or aliquoted and stored at -20C to avoid repeated freeze-thaw cycles, which can degrade the compound

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Excessive BDNF signaling has been associated with epileptiform activity in some research models