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The use of the in vitro comet assay with liver cell models can already be considered as part of an overall weight of evidence approach, but further optimization work, including expanded training sets of compounds and thorough validation of appropriate and ubiquitously available liver cell models would be required, before it could be incorporated into a standard battery for genotoxicity testing of NAs

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Evaluation of the antidepressant-like activity of Convolvulus pluricaulis Choisy in the mouse forced swim and tail suspension tests

Synaptogenesis and Neuroplasticity Dihexa's defining characteristic is its exceptional capacity to promote synaptogenesis and enhance neuroplasticity through activation of the HGF/c-Met receptor system

In breast cancer, a correlation between the copy number of the HER2 gene and sensitivity to Herceptin was seen [137]